Help move atopic dermatitis care forward:

Now enrolling
participants for a
Phase 2 clinical trial.

Find out if you may be eligible to participate

This clinical study tests whether ENV-294 is effective in treating moderate-to-severe atopic dermatitis.*

ENV-294 is an Investigational New Drug (IND). Participation in this study is voluntary and may not provide direct medical benefit.

From nature.
For Atopic Dermatitis.

Atopic dermatitis affects more than your skin. It can impact your comfort, confidence, and quality of life. ENV-294 is a new oral investigation medicine derived from a plant used for centuries to soothe skin conditions. This trial is testing how it may help people living with moderate-to-severe atopic dermatitis.

Find out if you may be eligible in less than 1 minute

Check if you may be eligible to participate

Some conditions may prevent people from joining; see details..

Key Exclusion Criteria

Individuals meeting any of the following conditions will not be eligible to participate:

  • Are pregnant or breast-feeding or are planning to become pregnant during the duration of the study for 90 days following the final dose of study drug.
  • Had a malignancy within the last 5 years, with the exception of successfully treated basal cell carcinoma.
  • Have clinically significant abnormalities in any of the clinical laboratory evaluations at screening or baseline as determined by the study doctor.
  • Are using any medications that may interfere with the study drug, its absorption, metabolism or the assessment of study results.
  • Have a history of alcohol abuse and/or illicit drug use within 12 months prior to dosing.
  • Have any uncontrolled current or recurrent illness (e.g., hepatitis B surface antigen, hepatitis C virus, or other condition) that could affect:
    • The action, absorption or disposition of the investigational product;
    • Clinical or laboratory assessments; or
    • Participant safety, including any significant concomitant disorder, major clinically significant depression as deemed by the study doctor, active bacterial, fungal, or viral infection, incompatible with participation in the study.
  • Have the presence of any skin conditions (e.g., psoriasis, seborrheic dermatitis) or have large tattoos that would interfere with clinical assessment, evaluation of AD, or treatment response.
  • Have an ongoing clinically significant skin infection or is receiving treatment for infection that may interfere with assessment of AD.

Answer 5 questions to see if you
may be eligible to participate

Participation benefits

Atopic dermatitis care from a study
doctor no insurance needed

Compensation for
time and travel

No cost car service to and
from the study site

Find a nearby location

      About the Company

      Enveda uses the power of nature to discover new medicines. The company combines plant science with advanced technology like artificial intelligence and chemistry tools to find and study natural components that could become new treatments for diseases.

      Our Mission

      FAQs

      What’s a clinical study?

      It’s how new medicines are discovered and proven to work. Every prescription today started with volunteer participants

      Why do people join?

      Some want to help others. Some hope new treatments might work for them. Many join to support science and to learn more about their own health.

      Who can participate?

      Men and women ages 18 to 75 with moderate-to-severe atopic dermatitis may qualify if diagnosed at least 12 months prior to the screening and have been flare-free for at least four weeks before screening as assessed by the study doctor. Participants must have a history of inadequate response or intolerance to topical corticosteroids or other topical treatments for AD as determined by the study doctor. Participants must agree to use an emollient (without urea) daily for at least 1 week prior to Day 1 (except on visit day before the visit) and agree to continue using that same emollient daily at the same frequency (ideally once or twice daily) throughout the study. Exclusions apply.

      Will I receive the investigational drug?

      This is a double blinded study, meaning some participants will receive the investigational drug while others will receive a placebo.

      Is it safe?

      Your safety comes first. The study is reviewed by an independent review board (IRB) and conducted by doctors who will monitor your health closely.

      Will my information be private?

      Your personal information will be kept confidential and de-identified whenever possible, unless required by law. The study doctor, the sponsor or persons working on behalf of the sponsor, and under certain circumstances, the United States Food and Drug Administration (FDA) and the Institutional Review Board (IRB) will be able to inspect and copy confidential study-related records which identify a participant by name.

      What's the time commitment?

      You’ll receive all details before joining, including the number of visits, how long each visit lasts, and the study duration.

      Are participants compensated?

      Yes. Participants may be compensated for their time and travel. The exact compensation amount is based on factors such as study-visit length, number of study visits, and travel distance.

      Can I change my mind?

      Yes, you can leave the study anytime, for any reason.

      What happens after the study ends?

      Upon completion, participants will resume ongoing medical care with their regular healthcare providers.