This research study is evaluating an investigational medication (ENV-294) for moderate-to-severe atopic dermatitis.*
Atopic dermatitis affects more than your skin. It can impact your comfort, confidence, and quality of life. ENV-294 is a new oral investigational medicine derived from a plant used for centuries to soothe skin conditions. This trial is testing how it may help people living with moderate-to-severe atopic dermatitis.
Some conditions may prevent people from joining; see details.
Key Exclusion Criteria
Individuals meeting any of the following conditions will not be eligible to participate:
Enveda uses the power of nature to discover new medicines. The company combines plant science with advanced technology like artificial intelligence and chemistry tools to find and study natural components that could become new treatments for diseases.
It’s how new medicines are discovered and proven to work. Every prescription today started with volunteer participants
Some want to help others. Some hope new treatments might work for them. Many join to support science and to learn more about their own health.
Men and women ages 18 to 75 with moderate-to-severe atopic dermatitis may qualify if diagnosed at least 12 months prior to the screening and have been flare-free for at least four weeks before screening as assessed by the study doctor. Participants must have a history of inadequate response or intolerance to topical corticosteroids or other topical treatments for AD as determined by the study doctor. Participants must agree to use an emollient (without urea) daily for at least 1 week prior to Day 1 (except on visit day before the visit) and agree to continue using that same emollient daily at the same frequency (ideally once or twice daily) throughout the study. Exclusions apply.
This is a double blinded study, meaning some participants will receive the investigational drug while others will receive a placebo.
Your safety comes first. The study is reviewed by an independent review board (IRB) and conducted by doctors who will monitor your health closely.
Your personal information will be kept confidential and de-identified whenever possible, unless required by law. The study doctor, the sponsor or persons working on behalf of the sponsor, and under certain circumstances, the United States Food and Drug Administration (FDA) and the Institutional Review Board (IRB) will be able to inspect and copy confidential study-related records which identify a participant by name.
You’ll receive all details before joining, including the number of visits, how long each visit lasts, and the study duration.
Yes. Participants may be compensated for their time and travel. The exact compensation amount is based on factors such as study-visit length, number of study visits, and travel distance.
Yes, you can leave the study anytime, for any reason.
Upon completion, participants will resume ongoing medical care with their regular healthcare providers.